Evidence-Based Dentistry Update on Silver Diamine Fluoride
- PMID: 30447792
- PMCID: PMC6500430
- DOI: 10.1016/j.cden.2018.08.011
Evidence-Based Dentistry Update on Silver Diamine Fluoride
Abstract
This article reviews current evidence on the effectiveness of silver diamine fluoride (SDF) as a caries arresting and preventive agent. It provides clinical recommendations around SDF's appropriate use as part of a comprehensive caries management program. Systematic reviews confirm that SDF is effective for caries arrest on cavitated lesions in primary teeth and root caries in the elderly. It may also prevent new lesions. Application is easy, noninvasive, affordable, and safe. Although it stains the lesions dark as it arrests them, it provides clinicians with an additional tool for caries management when esthetics are not a primary concern.
Keywords: Caries arrest; Caries management; Dental caries; Pediatric dentistry; Silver diamine fluoride.
Copyright © 2018 Elsevier Inc. All rights reserved.
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References
-
- Sheiham A, Williams DM, Weyant RJ, et al. Billions with oral disease: a global health crisis–a call to action. J Am Dent Assoc 2015;146(12):861–4. - PubMed
-
- Petersen PE, Lennon MA. Effective use of fluorides for the prevention of dental caries in the 21st century: the WHO approach. Community Dent Oral Epidemiol 2004;32(5):319–21. - PubMed
-
- Petersen PE, Ogawa H. Prevention of dental caries through the use of fluoride– the WHO approach. Community Dent Health 2016;33(2):66–8. - PubMed
-
- Bagramian RA, Garcia-Godoy F, Volpe AR. The global increase in dental caries. A pending public health crisis. Am J Dent 2009;22(1):3–8. - PubMed
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