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Case Reports
. 2019 Jan;45(1):101-104.
doi: 10.1016/j.jcrs.2018.08.036. Epub 2018 Nov 14.

Late-onset progression of keratoconus after therapy with selective tissue estrogenic activity regulator

Emilio A Torres-Netto  1 , J Bradley Randleman  2 , Nikki L Hafezi  3 , Farhad Hafezi  4
Affiliations
Case Reports

Late-onset progression of keratoconus after therapy with selective tissue estrogenic activity regulator

Emilio A Torres-Netto et al. J Cataract Refract Surg. 2019 Jan.

Abstract

We describe the association of rapid progression of keratoconus in a 49-year-old woman on selective tissue estrogenic activity regulator (STEAR) therapy for endometriosis. Approximately 4 months after initiation of therapy with STEAR therapy and 3 months after ovariectomy, Scheimpflug images showed a massive increase in the previously stable ectasia. During this period, the maximum increase in the keratometry values was 2.7 diopters (D) in the right eye and 3.8 D in the left eye. Corneal crosslinking (CXL) was performed in both eyes. This resulted in excessive flattening of 5.5 D in the right eye and 6.1 D in the left eye at 9 months postoperatively. Patients having STEAR therapy must be monitored closely for corneal changes.

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  • Reply.
    Torres-Netto EA, Randleman JB, Hafezi NL, Hafezi F. Torres-Netto EA, et al. J Cataract Refract Surg. 2019 Jul;45(7):1055. doi: 10.1016/j.jcrs.2019.04.037. J Cataract Refract Surg. 2019. PMID: 31262477 No abstract available.
  • Progression of keratoconus resulting from hormone replacement therapy.
    Natarajan R, Ravindran R. Natarajan R, et al. J Cataract Refract Surg. 2019 Jul;45(7):1055. doi: 10.1016/j.jcrs.2019.04.038. J Cataract Refract Surg. 2019. PMID: 31262478 No abstract available.

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