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Review
. 2018 Nov 19;16(1):108.
doi: 10.1186/s12958-018-0437-8.

Sport, doping and female fertility

Sandro La Vignera  1 , Rosita A Condorelli  2 , Rossella Cannarella  2 , Ylenia Duca  2 , Aldo E Calogero  2
Affiliations
Review

Sport, doping and female fertility

Sandro La Vignera et al. Reprod Biol Endocrinol. .

Abstract

This article is a review that addresses the following topics, divided by paragraphs. The first paragraph investigates the effects of physical activity on ovarian function, analyzing in particular the changes concerning the serum concentrations of follicle-stimulating hormone, luteinizing hormone, prolactin, growth hormone, thyroid hormones, leptin, ghrelin, neuropeptide Y. The second paragraph analyzes the effects of doping on the hypothalamic-pituitary-ovarian axis. Finally, the last paragraph analyzes the PCOS category, evaluating the effects of hyperandrogenism in relation to athletic performance.

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Not applicable.

Competing interests

The authors declare that they have no competing interests.

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References

    1. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81:19–25. - PubMed
    1. Sheid JL, De Souza MJ. Menstrual irregularities and Energy deficiency in physically active women: the role of ghrelin, PYY and adipocytokines. Med Sport Sci. 2010;55:82–102. doi: 10.1159/000321974. - DOI - PubMed
    1. Mircea CN, Lujan ME, Pierson RA. Metabolic fuel and clinical implications for female reproduction. J Obstet Gynaecol Can. 2007;29:887–902. doi: 10.1016/S1701-2163(16)32661-5. - DOI - PubMed
    1. Gifford RM, Reynolds RM, Greeves J, Anderson RA, Woods DR. Reproductive dysfunction and associated pathology in women undergoing military training. J R Army Med Corps. 2017;0:1–10. - PubMed
    1. Loucks AB, Thuma JR. Luteinizing hormone pulsatility is disrupted at a threshold of energy availability in regularly menstruating women. J Clin Endocrinol Metab. 2003;88:297–311. doi: 10.1210/jc.2002-020369. - DOI - PubMed

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