De-intensified treatment in human papillomavirus-positive oropharyngeal cancer

Johannes Christiaan Oosthuizen¹, Jaime Doody²

Affiliations

¹ Department of Otolaryngology, Head and Neck Surgery, Ipswich Hospital, Ipswich, QLD 4305, Australia; The University of Queensland, Faculty of Medicine, Herston, QLD, Australia. Electronic address: c.oosth@gmail.com.
² Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, MA, USA; Department of Otolaryngology, Harvard Medical School, Boston, MA, USA.

PMID: 30449624
DOI: 10.1016/S0140-6736(18)32930-1

Free article

Comment

De-intensified treatment in human papillomavirus-positive oropharyngeal cancer

Johannes Christiaan Oosthuizen et al. Lancet. 2019.

Free article

. 2019 Jan 5;393(10166):5-7.

doi: 10.1016/S0140-6736(18)32930-1. Epub 2018 Nov 15.

Authors

Johannes Christiaan Oosthuizen¹, Jaime Doody²

Affiliations

¹ Department of Otolaryngology, Head and Neck Surgery, Ipswich Hospital, Ipswich, QLD 4305, Australia; The University of Queensland, Faculty of Medicine, Herston, QLD, Australia. Electronic address: c.oosth@gmail.com.
² Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, MA, USA; Department of Otolaryngology, Harvard Medical School, Boston, MA, USA.

PMID: 30449624
DOI: 10.1016/S0140-6736(18)32930-1

Erratum in

Department of Error.
[No authors listed] [No authors listed] Lancet. 2019 Jan 5;393(10166):30. doi: 10.1016/S0140-6736(18)32969-6. Epub 2019 Jan 3. Lancet. 2019. PMID: 32146928 No abstract available.

No abstract available

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Comment on

Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial.
Mehanna H, Robinson M, Hartley A, Kong A, Foran B, Fulton-Lieuw T, Dalby M, Mistry P, Sen M, O'Toole L, Al Booz H, Dyker K, Moleron R, Whitaker S, Brennan S, Cook A, Griffin M, Aynsley E, Rolles M, De Winton E, Chan A, Srinivasan D, Nixon I, Grumett J, Leemans CR, Buter J, Henderson J, Harrington K, McConkey C, Gray A, Dunn J; De-ESCALaTE HPV Trial Group. Mehanna H, et al. Lancet. 2019 Jan 5;393(10166):51-60. doi: 10.1016/S0140-6736(18)32752-1. Epub 2018 Nov 15. Lancet. 2019. PMID: 30449623 Free PMC article. Clinical Trial.
Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial.
Gillison ML, Trotti AM, Harris J, Eisbruch A, Harari PM, Adelstein DJ, Jordan RCK, Zhao W, Sturgis EM, Burtness B, Ridge JA, Ringash J, Galvin J, Yao M, Koyfman SA, Blakaj DM, Razaq MA, Colevas AD, Beitler JJ, Jones CU, Dunlap NE, Seaward SA, Spencer S, Galloway TJ, Phan J, Dignam JJ, Le QT. Gillison ML, et al. Lancet. 2019 Jan 5;393(10166):40-50. doi: 10.1016/S0140-6736(18)32779-X. Epub 2018 Nov 15. Lancet. 2019. PMID: 30449625 Free PMC article. Clinical Trial.

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De-intensified treatment in human papillomavirus-positive oropharyngeal cancer

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De-intensified treatment in human papillomavirus-positive oropharyngeal cancer

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