TFEB, a master regulator of lysosome biogenesis and autophagy, is a new player in alcoholic liver disease
- PMID: 30450489
- PMCID: PMC6234977
- DOI: 10.21037/dmr.2018.09.03
TFEB, a master regulator of lysosome biogenesis and autophagy, is a new player in alcoholic liver disease
Conflict of interest statement
Conflicts of Interest: The authors have no conflicts of interest to declare.
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Comment on
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Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice.Gastroenterology. 2018 Sep;155(3):865-879.e12. doi: 10.1053/j.gastro.2018.05.027. Epub 2018 May 18. Gastroenterology. 2018. PMID: 29782848 Free PMC article.
References
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- Sardiello M, Palmieri M, di Ronza A, et al. A gene network regulating lysosomal biogenesis and function. Science 2009;325:473–7. - PubMed
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- Thomes PG, Trambly CS, Fox HS, et al. Acute and Chronic Ethanol Administration Differentially Modulate Hepatic Autophagy and Transcription Factor EB. Alcohol Clin Exp Res 2015;39:2354–63. - PubMed
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