Semiconducting polymer-based nanoparticles for photothermal therapy at the second near-infrared window

Zuwu Wei¹, Ming Wu¹, Shanyou Lan², Jiong Li³, Xiaolong Zhang¹, Da Zhang¹, Xiaolong Liu⁴, Jingfeng Liu⁵

Affiliations

¹ The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, P. R. China.
² The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, P. R. China.
³ The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and Department of Translational Medicine, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen 361024, P. R. China. xiaoloong.liu@gmail.com drjingfeng@126.com.
⁴ The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, P. R. China and Department of Translational Medicine, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen 361024, P. R. China. xiaoloong.liu@gmail.com drjingfeng@126.com.
⁵ The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, P. R. China and Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, P. R. China and Department of Translational Medicine, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen 361024, P. R. China. xiaoloong.liu@gmail.com drjingfeng@126.com.

PMID: 30451251
DOI: 10.1039/c8cc07583b

Semiconducting polymer-based nanoparticles for photothermal therapy at the second near-infrared window

Zuwu Wei et al. Chem Commun (Camb). 2018.

. 2018 Dec 14;54(96):13599-13602.

doi: 10.1039/c8cc07583b. Epub 2018 Nov 19.

Authors

Zuwu Wei¹, Ming Wu¹, Shanyou Lan², Jiong Li³, Xiaolong Zhang¹, Da Zhang¹, Xiaolong Liu⁴, Jingfeng Liu⁵

Affiliations

¹ The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, P. R. China.
² The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, P. R. China.
³ The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and Department of Translational Medicine, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen 361024, P. R. China. xiaoloong.liu@gmail.com drjingfeng@126.com.
⁴ The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, P. R. China and Department of Translational Medicine, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen 361024, P. R. China. xiaoloong.liu@gmail.com drjingfeng@126.com.
⁵ The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China and Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China and The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, P. R. China and Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, P. R. China and Department of Translational Medicine, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, Xiamen 361024, P. R. China. xiaoloong.liu@gmail.com drjingfeng@126.com.

PMID: 30451251
DOI: 10.1039/c8cc07583b

Abstract

We designed novel diketopyrrolopyrrole polymer based nanoparticles (DPP-IID-FA), which exhibited strong light absorption and excellent photothermal conversion in the NIR optical window, and displayed high biocompatibility and photostability. Furthermore, our nanoparticles could be efficiently uptaken by cancer cells and exhibited outstanding anticancer ability both in vitro and in vivo under NIR-II laser irradiation.

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Semiconducting polymer-based nanoparticles for photothermal therapy at the second near-infrared window

Affiliations

Semiconducting polymer-based nanoparticles for photothermal therapy at the second near-infrared window

Authors

Affiliations

Abstract

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Miscellaneous