Isolation and partial characterisation of a 26 kilodalton antigen from Plasmodium falciparum recognised by an inhibitory monoclonal antibody
- PMID: 3045539
- DOI: 10.1016/0166-6851(88)90067-9
Isolation and partial characterisation of a 26 kilodalton antigen from Plasmodium falciparum recognised by an inhibitory monoclonal antibody
Abstract
A 26 kDa protein, present in trophozoites and schizonts of Plasmodium falciparum, has been identified as the target of a monoclonal antibody that weakly inhibits parasite growth in vitro. The antigen has been purified to homogeneity by immuno-affinity chromatography and electrophoresis. The sequence of 19 amino acids at the N-terminus of the protein has been determined.
Similar articles
-
An epitope recognised by inhibitory monoclonal antibodies that react with a 51 kilodalton merozoite surface antigen in Plasmodium falciparum.Mol Biochem Parasitol. 1988 Feb;28(1):1-10. doi: 10.1016/0166-6851(88)90173-9. Mol Biochem Parasitol. 1988. PMID: 2453800
-
Identification and characterisation of proteins associated with the rhoptry organelles of Plasmodium falciparum merozoites.Parasitol Res. 1987;73(5):425-34. doi: 10.1007/BF00538200. Parasitol Res. 1987. PMID: 3309942
-
Plasmodium falciparum: characterization of a 33-kDa soluble antigen.Exp Parasitol. 1989 Apr;68(3):297-307. doi: 10.1016/0014-4894(89)90112-4. Exp Parasitol. 1989. PMID: 2467824
-
The 140/130/105 kilodalton protein complex in the rhoptries of Plasmodium falciparum consists of discrete polypeptides.Mol Biochem Parasitol. 1988 Jun;29(2-3):251-60. doi: 10.1016/0166-6851(88)90080-1. Mol Biochem Parasitol. 1988. PMID: 3045543
-
Inhibitory monoclonal antibodies to soluble Plasmodium falciparum antigens.Parasitol Res. 1987;73(6):518-23. doi: 10.1007/BF00535326. Parasitol Res. 1987. PMID: 2447580
Cited by
-
Antibody and clinical responses in volunteers to immunization with malaria peptide-diptheria toxoid conjugates.Clin Exp Immunol. 1995 Feb;99(2):168-74. doi: 10.1111/j.1365-2249.1995.tb05528.x. Clin Exp Immunol. 1995. PMID: 7851007 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources