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Comment
. 2018 Nov 19;47(4):400-401.
doi: 10.1016/j.devcel.2018.11.002.

Strengthening Microtubules by Cuts that Heal

Anna Akhmanova  1
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Free article
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Strengthening Microtubules by Cuts that Heal

Anna Akhmanova. Dev Cell. .
Free article

Abstract

Microtubule-severing enzymes, which can remove tubulin dimers from microtubule lattices, participate in cytoskeletal remodeling in various contexts. A recent study showed that partially damaged microtubule shafts and new microtubule ends generated by these enzymes can incorporate GTP-tubulin and serve as sites of microtubule rescue and re-growth, explaining how severing enzymes can amplify microtubule arrays.

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