Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Nov;23(46):1800578.
doi: 10.2807/1560-7917.ES.2018.23.46.1800578.

Prospective enterovirus D68 (EV-D68) surveillance from September 2015 to November 2018 indicates a current wave of activity in Wales

Simon Cottrell  1   2 , Catherine Moore  2   3 , Malorie Perry  1 , Ember Hilvers  1 , Chris Williams  1 , Ananda Giri Shankar  1
Affiliations

Prospective enterovirus D68 (EV-D68) surveillance from September 2015 to November 2018 indicates a current wave of activity in Wales

Simon Cottrell et al. Euro Surveill. 2018 Nov.

Abstract

Since 7 June 2018, an enterovirus D-68 (EV-D68) season (the third since 2015) is ongoing in Wales, with 114 confirmed cases thus far. Median age of the 220 cases since 2015 is 2.5 years (2.5 years in intensive care cases), 94% were hospitalised, 17% (n = 38) in intensive care. All had respiratory symptoms; bronchiolitis symptoms were reported in 60 cases, severe respiratory symptoms in 23 and acute flaccid myelitis in two cases.

Keywords: D68; acute flaccid myelitis; enterovirus; respiratory; surveillance.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure
Figure
Confirmed enterovirus D-68 cases, Wales, week 35 2015–week 44 2018 (n = 220)
See this image and copyright information in PMC

References

    1. Williams CJ, Thomas RH, Pickersgill TP, Lyons M, Lowe G, Stiff RE, et al. Cluster of atypical adult Guillain-Barré syndrome temporally associated with neurological illness due to EV-D68 in children, South Wales, United Kingdom, October 2015 to January 2016. Euro Surveill. 2016;21(4):30119. 10.2807/1560-7917.ES.2016.21.4.30119 - DOI - PubMed
    1. Poelman R, Schuffenecker I, Van Leer-Buter C, Josset L, Niesters HGM, Lina B, ESCV-ECDC EV-D68 study group European surveillance for enterovirus D68 during the emerging North-American outbreak in 2014. J Clin Virol. 2015;71:1-9. 10.1016/j.jcv.2015.07.296 - DOI - PubMed
    1. Nix WA, Oberste MS, Pallansch MA. Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens. J Clin Microbiol. 2006;44(8):2698-704. 10.1128/JCM.00542-06 - DOI - PMC - PubMed
    1. Holm-Hansen CC, Midgley SE, Schjørring S, Fischer TK. The importance of enterovirus surveillance in a Post-polio world. Clin Microbiol Infect. 2017;23(6):352-4. 10.1016/j.cmi.2017.02.010 - DOI - PubMed
    1. Harvala H, Broberg E, Benschop K, Berginc N, Ladhani S, Susi P, et al. Recommendations for enterovirus diagnostics and characterisation within and beyond Europe. J Clin Virol. 2018;101:11-7. 10.1016/j.jcv.2018.01.008 - DOI - PubMed

MeSH terms

LinkOut - more resources