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. 2018 Dec 3;215(12):2955-2958.
doi: 10.1084/jem.20182042. Epub 2018 Nov 20.

All (animal) models (of neurodegeneration) are wrong. Are they also useful?

Richard M Ransohoff  1   2
Affiliations

All (animal) models (of neurodegeneration) are wrong. Are they also useful?

Richard M Ransohoff. J Exp Med. .

Abstract

Richard M. Ransohoff, Entrepreneur-in-Residence at Third Rock Ventures and Visiting Scientist at Harvard Medical School, provides his personal opinion on using animal models to address current challenges and opportunities in drug development for neurodegeneration.

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Figures

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Use of animal models across the process of drug development. The cartoon indicates selected stages of drug development for which animal models may be applied. ADME: Absorption, Distribution, Metabolism, and Excretion.
See this image and copyright information in PMC

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