Seq-ing out the Killers of Mice and Men
- PMID: 30462994
- DOI: 10.1016/j.immuni.2018.11.007
Seq-ing out the Killers of Mice and Men
Abstract
The diversity of natural killer cells between mouse and human is poorly understood. In this issue of Immunity, Crinier et al. (2018) utilize single-cell RNA-seq to profile splenic and blood NK cells from both organisms, uncovering both tissue- and species-specific transcriptomic signatures.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice.Immunity. 2018 Nov 20;49(5):971-986.e5. doi: 10.1016/j.immuni.2018.09.009. Epub 2018 Nov 6. Immunity. 2018. PMID: 30413361 Free PMC article.
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