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Comment
. 2018 Nov 20;49(5):798-800.
doi: 10.1016/j.immuni.2018.11.009.

Mets and NETs: The Awakening Force

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Free article
Comment

Mets and NETs: The Awakening Force

Victoria Sanz-Moreno et al. Immunity. .
Free article

Abstract

In a recent study published in Science, Albrengues et al. (2018) unveil an intriguing mechanism whereby the release of neutrophil extra-cellular traps during chronic lung inflammation awakens dormant malignant cells and contributes to cancer progression.

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  • Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice.
    Albrengues J, Shields MA, Ng D, Park CG, Ambrico A, Poindexter ME, Upadhyay P, Uyeminami DL, Pommier A, Küttner V, Bružas E, Maiorino L, Bautista C, Carmona EM, Gimotty PA, Fearon DT, Chang K, Lyons SK, Pinkerton KE, Trotman LC, Goldberg MS, Yeh JT, Egeblad M. Albrengues J, et al. Science. 2018 Sep 28;361(6409):eaao4227. doi: 10.1126/science.aao4227. Science. 2018. PMID: 30262472 Free PMC article.