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. 2019 Feb 25;57(3):312-316.
doi: 10.1515/cclm-2018-0610.

Liquid biopsy: novel technologies and clinical applications

Natalie Reimers  1 , Klaus Pantel  2
Affiliations
Free article

Liquid biopsy: novel technologies and clinical applications

Natalie Reimers et al. Clin Chem Lab Med. .
Free article

Abstract

"Liquid biopsy" was introduced as a new diagnostic concept in 2010 for the analysis of circulating tumor cells (CTCs) and has been now extended to material (in particular DNA) released by tumor cells in the peripheral blood of cancer patients. Over the past decade, various methods have been developed to detect CTCs and ctDNA in the peripheral blood of cancer patients.

Keywords: circulating tumor cells; liquid biopsy; minimal residual disease.

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