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Comment
. 2018 Dec;94(6):1048-1050.
doi: 10.1016/j.kint.2018.09.006.

Expanding the spectrum of APOL1-related renal disease: de novo collapsing glomerulopathy following kidney transplant

Jeffrey B Kopp  1
Affiliations
Comment

Expanding the spectrum of APOL1-related renal disease: de novo collapsing glomerulopathy following kidney transplant

Jeffrey B Kopp. Kidney Int. 2018 Dec.

Abstract

Santoriello et al. report a series of 38 cases of de novo collapsing glomerulopathy following kidney transplant. Associations included acute rejection, viral infection, and APOL1 high-risk genotype (the latter in 9 cases). Risk factors for collapsing glomerulopathy included acute rejection, viral infection, acute vaso-occlusive disease, and an African American donor. The data are suggestive of, but do not directly establish, a role for interferon in these associations.

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References

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