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Review
. 2019 Jun;105(6):1300-1302.
doi: 10.1002/cpt.1260. Epub 2018 Nov 22.

The Case for Pharmacogenetics-Guided Prescribing of Codeine in Children

Roseann S Gammal  1   2 , Kelly E Caudle  2 , Charles T Quinn  3 , Winfred C Wang  4 , Andrea Gaedigk  5 , Cynthia A Prows  6 , Cyrine E Haidar  2 , Annette K Taylor  7 , Teri E Klein  8 , Katrin Sangkuhl  8 , Jane S Hankins  4 , Kristine R Crews  2
Affiliations
Review

The Case for Pharmacogenetics-Guided Prescribing of Codeine in Children

Roseann S Gammal et al. Clin Pharmacol Ther. 2019 Jun.
No abstract available

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Conflict of interest statement

CONFLICTS OF INTEREST/DISCLOSURE

AKT is the Scientific Director of Molecular Genetics at the Laboratory Corporation of America Holdings.

References

    1. Crews KR et al. Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update. Clin Pharmacol Ther 95, 376–82 (2014). - PMC - PubMed
    1. Safety review update of codeine use in children; new Boxed Warning and Contraindication on use after tonsillectomy and/or adenoidectomy <https://www.fda.gov/downloads/Drugs/DrugSafety/UCM339116.pdf> (2013). Accessed May 29 2018.
    1. Code of Federal Regulations Title 21. <https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?f...>. Accessed Sept 21 2017.
    1. Gammal RS et al. Pharmacogenetics for Safe Codeine Use in Sickle Cell Disease. Pediatrics 138, (2016). - PMC - PubMed
    1. NHGRI. The Cost of Sequencing a Human Genome. <https://www.genome.gov/27565109/the-cost-of-sequencing-a-human-genome/>. Accessed Oct 30 2017.