Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Dec;78(18):1931-1937.
doi: 10.1007/s40265-018-1015-2.

Omadacycline: First Global Approval

Anthony Markham  1 , Susan J Keam  2
Affiliations
Review

Omadacycline: First Global Approval

Anthony Markham et al. Drugs. 2018 Dec.

Abstract

Paratek Pharmaceuticals are developing omadacycline (NUZYRA™), a first-in-class orally active aminomethylcycline antibacterial, as a treatment for various bacterial infections. The drug, which is available in intravenous and oral formulations, has a broad spectrum of antibacterial activity and was recently approved in the USA as a treatment for the treatment of community acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI) in adults. This article summarizes the milestones in the development of omadacycline leading to this first global approval for the treatment of CABP and ABSSSI.

PubMed Disclaimer

References

    1. Antimicrob Agents Chemother. 2012 Nov;56(11):5650-4 - PubMed
    1. Antimicrob Agents Chemother. 2014;58(3):1279-83 - PubMed
    1. Bioorg Med Chem. 2016 Dec 15;24(24):6409-6419 - PubMed
    1. Antimicrob Agents Chemother. 2017 Apr 24;61(5): - PubMed
    1. Antimicrob Agents Chemother. 2017 Apr 24;61(5): - PubMed

MeSH terms

LinkOut - more resources