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. 2018 May-Aug;12(2):85-89.
doi: 10.5005/jp-journals-10008-1249. Epub 2018 Aug 1.

Deep Sclerectomy with Porous Collagen in Open-angle Glaucoma, Short-term Study

Ahmed Elbably  1 , Tageldin M Othman  2 , Ahmed Mousa  3 , Mohammed Elridy  4 , Wesam Badawy  5 , Mohammed Elbably  6
Affiliations

Deep Sclerectomy with Porous Collagen in Open-angle Glaucoma, Short-term Study

Ahmed Elbably et al. J Curr Glaucoma Pract. 2018 May-Aug.

Abstract

Aim: To assess the role of porous collagen in deep sclerectomy (DS), with and without trabeculo-Descemet membrane (TDM) rupture.

Patients and methods: Forty-six eyes with different types of open-angle glaucoma and medically uncontrolled intraocular pressure (IOP) were selected. DS was performed in all cases. Ologen was implanted as a single large piece in the scleral lake and subconjunctival space in all cases with and without TDM rupture.

Results: A total sample of 46 open-angle glaucoma patients were included in the study. The mean ± standard deviation (SD) IOP was 25.6 mm Hg ± 10.6 (range 12-58 mm Hg) pre-operatively. On follow-up, the mean ± SD IOP was 6.1 mm Hg ± 3.7 (range 2-20 mm Hg) 1 day postoperatively and 9.3 mm Hg ± 4.0 (range 4-23 mm Hg) after 1 month of follow-up, at 12 months the IOP was at 12.1 mm Hg ± 3 (range 8-18 mm Hg). The overall mean ± SD IOP reduction percentage was 48.3% ± 21.3 (range 0.0-86.2). Comparing mean IOP reductions at last follow-up between TDM rupture cases and non-TDM cases (Mann-Whitney test), the mean ± SD IOP reduction in TDM rupture patients was 12.1 ± 8.0 mm Hg (range 2-27) meanwhile, in non-TDM rupture patients it was 14.3 ± 11.4 mm Hg (range 0-50). However, the difference in IOP reduction between the two groups was not significant. (p = 0.689).

Conclusion: Porous collagen can enhance the results of DS; also, it helps to proceed with DS in cases of TDM rupture without converting to trabeculectomy.How to cite this article: Elbably A, Othman TM, Mousa A, Elridy M, Badawy W, Elbably M. Deep Sclerectomy with Porous Collagen in Open-angle Glaucoma, Short-term Study. J Curr Glaucoma Pract 2018;12(2):85-89.

Keywords: Glaucoma; Ologen.; DS.

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Conflict of interest statement

Source of support: Nil Conflict of interest: None

Figures

Fig. 1:
Fig. 1:
Deep sclerectomy with wide trabeculodescemet window
Fig. 2:
Fig. 2:
Ologen in both scleral lake and subconjunctival space
Fig. 3:
Fig. 3:
IOP periodic readings
Fig. 4:
Fig. 4:
Visual acuity periodic readings
See this image and copyright information in PMC

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