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. 2018 Nov 9;33(48):e309.
doi: 10.3346/jkms.2018.33.e309. eCollection 2018 Nov 26.

National Registry Data from Korean Neonatal Network: Two-Year Outcomes of Korean Very Low Birth Weight Infants Born in 2013-2014

YoungAh Youn  1 , Soon Min Lee  2 , Jong-Hee Hwang  3 , Su Jin Cho  4 , Ee-Kyung Kim  5 , Ellen Ai-Rhan Kim  6 ; Korean Neonatal Network
Affiliations

National Registry Data from Korean Neonatal Network: Two-Year Outcomes of Korean Very Low Birth Weight Infants Born in 2013-2014

YoungAh Youn et al. J Korean Med Sci. .

Abstract

Background: The aim of this study was to observe long-term outcomes of very low birth weight infants (VLBWIs) born between 2013 and 2014 in Korea, especially focusing on neurodevelopmental outcomes.

Methods: The data were collected from Korean Neonatal Network (KNN) registry from 43 and 54 participating units in 2013 and 2014, respectively. A standardized electronic case report form containing 30 items related to long-term follow up was used after data validation.

Results: Of 2,660 VLBWI, the mean gestational age and birth weight were 291/7 ± 26/7 weeks and 1,093 ± 268 g in 2013 and 292/7 ± 26/7 weeks and 1,125 ± 261 g in 2014, respectively. The post-discharge mortality rate was 1.2%-1.5%. Weight < 50th percentile was 46.5% in 2013 and 66.1% in 2014. The overall prevalence of cerebral palsy among the follow up infants was 6.2% in 2013 and 6.6% in 2014. The Bayley Scales of Infant Developmental Outcomes version II showed 14%-25% of infants had developmental delay and 3%-8% of infants in Bayley version III. For the Korean developmental screening test for infants and children, the area "Further evaluation needed" was 5%-12%. Blindness in both eyes was reported to be 0.2%-0.3%. For hearing impairment, 0.8%-1.9% showed bilateral hearing loss. Almost 50% were readmitted to hospital with respiratory illness as a leading cause.

Conclusion: The overall prevalence of long-term outcomes was not largely different among the VLBWI born between 2013 and 2014. This study is the first large national data study of long-term outcomes.

Keywords: Cerebral Palsy; Incidence; Neurodevelopmental Outcome; Very Low Birth Weight Infants.

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Conflict of interest statement

Disclosure: The authors have no potential conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1. CP according to GA in VLBWI born in 2013. The above figure was abstracted from 2013 KNN annual reports.
CP = cerebral palsy, GA = gestational age, KNN = Korean Neonatal Network.
Fig. 2
Fig. 2. CP according to GA in VLBWI born in 2014. The above figure was abstracted from 2014 KNN annual reports.
CP = cerebral palsy, GA = gestational age, KNN = Korean Neonatal Network.
See this image and copyright information in PMC

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