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. 2016;62(4):471-8.

[Genetic disorders in primary brain glioblastomas]

[Article in Russian]
T R Izmailov, G P Snigireva, L V Shishkina, V A Solodky, G A Panshin, A Y Golanov, V M Sotnikov
  • PMID: 30475532

[Genetic disorders in primary brain glioblastomas]

[Article in Russian]
T R Izmailov et al. Vopr Onkol. 2016.

Abstract

Glioblastomas are characterized by a variety of genetic and epigenetic disorders, identification of which allows constantly expanding a list of genes directly involved in carcinogenesis, thus increasing molecular diagnostics, monitoring and predicting disease. Molecular-genetic studies of patients with glioblastomas allowed revealing changes relevant to this disease and determining their prognostic significance. In the future molecular-biological markers along with clinical and therapeutic factors may play a role of separate and independent factors of prognosis in patients with malignant brain lesions.

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