[Current state regarding fertility cryopreservation in pre-pubertal boys]

Abstract

Some treatments for any cancer therapy and hematological diseases may have gonadotoxic side effects that can result in infertility, and thus sperm cryopreservation is routinely offered to patients as the strategy to preserve their fertility. However, there are many cases where sperm banking cannot be applied, as is the case of pre-pubertal cancer patients and others unable to produce mature gametes at the moment of diagnosis. Regarding this, recent breakthroughs have gained public attention to the fertility preservation options that Regenerative Medicine can offer to these patients. In this review, we tried to compile and discuss the latest updates about all these strategies from a critical point of view.

Keywords: Criopreservación de tejido testicular inmaduro; Cryopreservation of immature testicular tissue; Espermatogénesis in vitro; Fertility preservation; Germ cell transplantation; In vitro spermatogenesis; Injerto testicular; Preservación de la fertilidad; Testicular grafting; Trasplante de células germinales.