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. 2018 Nov 27;8(1):17414.
doi: 10.1038/s41598-018-35836-z.

Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage

Siddharth Priyadarshi  1   2 , Nanishankar V Harohally  1   2 , C Roopavathi  3 , Madeneni Madhava Naidu  4   5
Affiliations

Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage

Siddharth Priyadarshi et al. Sci Rep. .

Abstract

Coriander foliage is a distinctive spice employed on a daily basis in curry and other Indian traditional food preparations mainly for the unique flavour attributes and health benefits. Radical scavenging activity has been demonstrated previously for coriander foliage. However, specific molecules responsible were not identified. A new molecule was isolated via chromatographic technique, and its structure was established by employing multinuclei and multidimensional NMR and HRMS techniques. The identified molecule Heneicos-1-ene was also screened for radical scavenging activity and antimicrobial activity, wherein it displayed radical scavenging activity of 89.6 ± 0.62% at 200 ppm, and also exhibited substantial antimicrobial activity against E. coli and Salmonella typhi.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
HRMS ESI-negative mode spectrum of Heneicos-1-ene.
Figure 2
Figure 2
13C NMR spectrum of Heneicos-1-ene.
Figure 3
Figure 3
The HMBC spectrum of Heneicos-1-ene.
Figure 4
Figure 4
Structure of molecule identified: Heneicos-1-ene.
Figure 5
Figure 5
Radical scavenging activity of Heneicos-1-ene and BHA at various concentrations.
Figure 6
Figure 6
Antibacterial activity of Heneicos-1-ene against (a) E. coli and (b) Salmonella typhi.
See this image and copyright information in PMC

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