Short Tear Film Breakup Time-Type Dry Eye
- PMID: 30481808
- DOI: 10.1167/iovs.17-23746
Short Tear Film Breakup Time-Type Dry Eye
Abstract
Measurement of tear film breakup time (TBUT) has become a standard diagnostic procedure in the dry eye clinic. Short TBUT-type dry eye is characterized by TBUT of less than 5 seconds and dry eye symptoms such as ocular fatigue or dryness; the importance of this type has recently been gaining prominence. Patients with this condition show no reduction in tear production and no staining of the ocular surface. The severity of symptoms is almost the same as in dry eye in which the ocular surface is stained with rose bengal or fluorescein. In addition to discomfort, patients suffer from decreased vision due to the unstable tear film, which can be attributed to the relative abnormality of the lipid layer, aqueous layer, and/or mucin layer. The diagnosis should be performed carefully on the basis of the patient's symptoms and the TBUT test, because the ocular surface appears normal and remains unstained.
Similar articles
-
Comparative Evaluation of Clinical Methods of Tear Film Stability Assessment: A Randomized Crossover Trial.JAMA Ophthalmol. 2018 Mar 1;136(3):291-294. doi: 10.1001/jamaophthalmol.2017.6489. JAMA Ophthalmol. 2018. PMID: 29392287 Free PMC article. Clinical Trial.
-
Evaluation of the clinical course of dry eye syndrome.Arch Ophthalmol. 2003 Oct;121(10):1364-8. doi: 10.1001/archopht.121.10.1364. Arch Ophthalmol. 2003. PMID: 14557170
-
Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation.Cornea. 1998 Jan;17(1):38-56. doi: 10.1097/00003226-199801000-00007. Cornea. 1998. PMID: 9436879 Clinical Trial.
-
Tear-film-oriented diagnosis for dry eye.Jpn J Ophthalmol. 2019 Mar;63(2):127-136. doi: 10.1007/s10384-018-00645-4. Epub 2019 Feb 19. Jpn J Ophthalmol. 2019. PMID: 30783943 Review.
-
Contact Lens-Associated Dry Eye Disease: Recent Advances Worldwide and in Japan.Invest Ophthalmol Vis Sci. 2018 Nov 1;59(14):DES102-DES108. doi: 10.1167/iovs.17-23685. Invest Ophthalmol Vis Sci. 2018. PMID: 30481813 Review.
Cited by
-
A Comprehensive Assessment of Tear-Film-Oriented Diagnosis (TFOD) in a Dacryoadenectomy Dry Eye Model.Int J Mol Sci. 2023 Nov 20;24(22):16510. doi: 10.3390/ijms242216510. Int J Mol Sci. 2023. PMID: 38003700 Free PMC article.
-
Short tear film breakup time-type of dry eye in India.Indian J Ophthalmol. 2021 Dec;69(12):3463-3468. doi: 10.4103/ijo.IJO_327_21. Indian J Ophthalmol. 2021. PMID: 34826975 Free PMC article.
-
Advances in clinical examination of lacrimal gland.Front Med (Lausanne). 2023 Aug 31;10:1257209. doi: 10.3389/fmed.2023.1257209. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37720501 Free PMC article. Review.
-
Effects of a Long-Acting Diquafosol Ophthalmic Solution on the Ocular Surface, Tolerability, and Usability in Dry Eye Disease.Adv Ther. 2024 Jun;41(6):2477-2485. doi: 10.1007/s12325-024-02871-4. Epub 2024 May 6. Adv Ther. 2024. PMID: 38709396
-
The effects of lutein/ zeaxanthin (Lute-gen®) on eye health, eye strain, sleep quality, and attention in high electronic screen users: a randomized, double-blind, placebo-controlled study.Front Nutr. 2025 Feb 3;12:1522302. doi: 10.3389/fnut.2025.1522302. eCollection 2025. Front Nutr. 2025. PMID: 39963662 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical