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. 1988 Sep 15;155(2):608-14.
doi: 10.1016/s0006-291x(88)80538-2.

Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein

G G Glenner  1 , E D Eanes, C A Wiley
Affiliations

Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein

G G Glenner et al. Biochem Biophys Res Commun. .

Abstract

A synthetic peptide formed from residues 20-29 of the pancreatic islet amyloid protein has the confirmation of a twisted beta-pleated sheet protein suggesting it is a potential contributor toward amyloid fibril formation in the islets of Langerhans in Type 2 diabetes mellitus.

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