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Comment
. 2018 Nov 27;2(22):3193-3195.
doi: 10.1182/bloodadvances.2018027078.

Comment on model-based meta-analysis to evaluate optimal doses of direct oral factor Xa inhibitors in atrial fibrillation patients

Stefan Willmann  1 , Liping Zhang  2 , Hannah Mayer  3 , Hans-Ulrich Siegmund  3 , Takahiko Tanigawa  4 , Masato Kaneko  4 , Gary Peters  5 , Jeffrey I Weitz  6   7 , Scott D Berkowitz  8 , Rolf Burghaus  1
Affiliations
Comment

Comment on model-based meta-analysis to evaluate optimal doses of direct oral factor Xa inhibitors in atrial fibrillation patients

Stefan Willmann et al. Blood Adv. .
No abstract available

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Conflict of interest statement

Conflict-of-interest disclosure: S.W., R.B., H.M., and H.-U.S. are employees of Bayer AG. R.B., H.M., and H.-U.S. own stock in Bayer AG. L.Z. and G.P. are employees of Janssen Research & Development LLC and own stock in Johnson & Johnson. J.I.W. is a consultant for and has received honoraria from Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Daiichi Sankyo, Ionis, Janssen, Merck, Novartis, Pfizer, and Portola. S.D.B. is an employee of Bayer US LLC. T.T. and M.K. are employees of Bayer Yakuhin Ltd.

Figures

Figure 1.
Figure 1.
Associations between model-estimated PT ratio, mean CHADS2score, and risk of major bleeding events. Population means of the time average of the PT ratio were digitized from Figure 2B and mean CHADS2 scores and probability of event were taken from Table 1 in Yoshioka et al.
See this image and copyright information in PMC

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References

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