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Review
. 2018 Nov;21(11):1091-1099.
doi: 10.22038/IJBMS.2018.31243.7529.

Saffron (Crocus sativus) petal as a new pharmacological target: a review

Azar Hosseini  1 , Bibi Marjan Razavi  2   3 , Hossein Hosseinzadeh  3   4
Affiliations
Review

Saffron (Crocus sativus) petal as a new pharmacological target: a review

Azar Hosseini et al. Iran J Basic Med Sci. 2018 Nov.

Abstract

Saffron petal is the main by-product of saffron processing which produced at high level but it is not applied and thrown out. Saffron petal is containing of several compounds such as mineral agents, anthocyanins, flavonoids, glycosides, alkaloids and kaempferol. As saffron petal is cheaper and produces in large amounts compared to saffron stigma, so, it can be considered as an appropriate source for different purposes. In this review different pharmacological properties of saffron petal such as anti-bacterial, anti-spasmodic, immunomodulatory, anti-tussive, anti-depressant, anti-nociceptive, hepato-protective, reno-protective, anti-hypertensive, anti-diabetic and anti-oxidant activity have been introduced. According to these properties, saffron petal can be used as an alternative or supplementary medicine in some diseases.

Keywords: Antidepressant; Crocus sativus; Hepatoprotective; Kaempferol; Metabolic syndrome; Saffron petal.

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Figures

Figure 1
Figure 1
Chemical structures of some major bioactive constituents of saffron petal. A) kaempferol; B)crocin; C)crocetin; D) kinsenoside; E) goodyeroside A; F) crocusatin-K; G) crocusatin-L
Figure 2
Figure 2
The pharmacological effects of saffron petal
See this image and copyright information in PMC

References

    1. Fernández J-A. Biology, biotechnology and biomedicine of saffron. Recent Res Dev Plant Sci. 2004;2:127–159.
    1. Rios J, Recio M, Giner R, Manez S. An update review of saffron and its active constituents. Phytother Res. 1996;10:189–193.
    1. Schmidt M, Betti G, Hensel A. Saffron in phytotherapy: pharmacology and clinical uses. Wien Med Wochenschr. 2007;157:315–319. - PubMed
    1. Hosseinzadeh H, Nassiri‐Asl M. Avicenna's (Ibn Sina) the canon of medicine and saffron (Crocus sativus): a review. Phytother Res. 2013;27:475–83. - PubMed
    1. Mollazadeh H, Emami SA, Hosseinzadeh H. Razi’s Al-Hawi and saffron (Crocus sativus): a review. Iran J Basic Med Sci. 2015;18:1153–1166. - PMC - PubMed

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