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. 2018 Oct 30;43(4):e45.
doi: 10.5395/rde.2018.43.e45. eCollection 2018 Nov.

Effect of casein phosphopeptide-amorphous calcium phosphate on fluoride release and micro-shear bond strength of resin-modified glass ionomer cement in caries-affected dentin

Jamila Nuwayji Agob  1 , Neven Saad Aref  2 , Essam El Saeid Al-Wakeel  2
Affiliations

Effect of casein phosphopeptide-amorphous calcium phosphate on fluoride release and micro-shear bond strength of resin-modified glass ionomer cement in caries-affected dentin

Jamila Nuwayji Agob et al. Restor Dent Endod. .

Erratum in

Abstract

Objectives: This study was conducted to evaluate fluoride release and the micro-shear bond strength of resin-modified glass ionomer cement (RMGIC) in casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)-remineralized caries-affected dentin (CAD).

Materials and methods: Exposed dentin surfaces of 30 human third molar teeth were divided into 2 equal groups for evaluating fluoride release and the micro-shear bond strength of RMGIC to CAD. Each group was subdivided into 3 equal subgroups: 1) control (sound dentin); 2) artificially demineralized dentin (CAD); 3) CPP-ACP remineralized dentin (remineralized CAD). To measure fluoride release, 15 disc-shaped specimens of RMGIC (4 mm in diameter and 2 mm in thickness) were bonded on one flat surface of the dentin discs of each group. Fluoride release was tested using ion chromatography at different intervals; 24 hours, 3, 5, 7 days. RMGIC micro-cylinders were built on the flat dentin surface of the 15 discs, which were prepared according to the assigned group. Micro-shear bond strength was measured after 24 hours water storage. Data were analyzed using 1- and 2-way analysis of variance and the post hoc least significant difference test (α = 0.05).

Results: Fluoride detected in solutions (at all intervals) and the micro-shear bond strength of RMGIC bonded to CPP-ACP-remineralized dentin were significantly higher than those bonded to artificial CAD (p < 0.05).

Conclusions: Demineralized CAD consumes more fluoride released from RMGIC into the solution for remineralization than CPP-ACP mineralized dentin does. CPP-ACP increases the micro-shear bond strength of RMGIC to CAD.

Keywords: CPP-ACP; Fluoride release; GIC.

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Conflict of interest statement

Conflict of Interest: No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1. Experimental design of this study.
RMGIC, resin-modified glass ionomer cement; CAD, caries-affected dentin; CPP-ACP, casein phosphopeptide-amorphous calcium phosphate.
See this image and copyright information in PMC

References

    1. Llena C, Leyda A, Forner L, Garcet S. Association between the number of early carious lesions and diet in children with a high prevalence of caries. Eur J Paediatr Dent. 2015;16:7–12. - PubMed
    1. Pereira PN, Nunes MF, Miguez PA, Swift EJ., Jr Bond strengths of a 1-step self-etching system to caries-affected and normal dentin. Oper Dent. 2006;31:677–681. - PubMed
    1. Mount GJ, Ngo H. Minimal intervention: a new concept for operative dentistry. Quintessence Int. 2000;31:527–533. - PubMed
    1. Zhong B, Peng C, Wang G, Tian L, Cai Q, Cui F. Contemporary research findings on dentine remineralization. J Tissue Eng Regen Med. 2015;9:1004–1016. - PubMed
    1. Rahiotis C, Vougiouklakis G. Effect of a CPP-ACP agent on the demineralization and remineralization of dentine in vitro . J Dent. 2007;35:695–698. - PubMed

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