Characterization of the human natural killer (NK) cell in blood and lymphoid organs
- PMID: 304845
- DOI: 10.1002/ijc.2910210109
Characterization of the human natural killer (NK) cell in blood and lymphoid organs
Abstract
The human natural killer (NK) cell in peripheral blood is a non-thymus-dependent, (Fc+ C3-), Ig-bearing lymphocyte and is probably identical to the human K cell, although not requiring the Fc receptor, in contrast to the K cell, for the lytic process. The human NK cell in tonsil and lymph node, on the other hand, is a non-Ig- bearing T lymphocyte, lacking both Fc and C3 receptors.
Similar articles
-
Surface characteristics of the human K (killer) lymphocyte.Int Arch Allergy Appl Immunol. 1977;55(1-6):112-25. doi: 10.1159/000231917. Int Arch Allergy Appl Immunol. 1977. PMID: 304041
-
The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic.J Immunol. 2004 Feb 1;172(3):1455-62. doi: 10.4049/jimmunol.172.3.1455. J Immunol. 2004. PMID: 14734722
-
Human natural cytotoxicity in the blood and lymphoid organs of healthy donors and patients with malignant disease.Int J Cancer. 1978 Jan 15;21(1):35-41. doi: 10.1002/ijc.2910210108. Int J Cancer. 1978. PMID: 342425
-
Working in "NK Mode": Natural Killer Group 2 Member D and Natural Cytotoxicity Receptors in Stress-Surveillance by γδ T Cells.Front Immunol. 2018 Apr 24;9:851. doi: 10.3389/fimmu.2018.00851. eCollection 2018. Front Immunol. 2018. PMID: 29740448 Free PMC article. Review.
-
[K (killer) and NK (natural killer) cells: characteristics, functions and biological properties (author's transl)].Wien Klin Wochenschr. 1980 Feb 29;92(5):147-56. Wien Klin Wochenschr. 1980. PMID: 6156545 Review. German.
Cited by
-
The nature of the natural killer (NK) cell of human intestinal mucosa and mesenteric lymph node.Clin Exp Immunol. 1985 Jul;61(1):160-8. Clin Exp Immunol. 1985. PMID: 2412737 Free PMC article.
-
Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.Br J Cancer. 1981 Aug;44(2):166-76. doi: 10.1038/bjc.1981.167. Br J Cancer. 1981. PMID: 6268135 Free PMC article.
-
Spontaneous and antibody-dependent cell-mediated cytotoxicity by human T cell subpopulations.Proc Natl Acad Sci U S A. 1978 Oct;75(10):5137-41. doi: 10.1073/pnas.75.10.5137. Proc Natl Acad Sci U S A. 1978. PMID: 311006 Free PMC article.
-
Native and inducible levels of natural cytotoxicity in lymph nodes draining mammary carcinoma.Cancer Immunol Immunother. 1983;15(1):32-8. doi: 10.1007/BF00199459. Cancer Immunol Immunother. 1983. PMID: 6553505 Free PMC article.
-
Natural killer cells: artifact to reality: an odyssey in biology.Cancer Metastasis Rev. 1983;2(4):323-36. doi: 10.1007/BF00048565. Cancer Metastasis Rev. 1983. PMID: 6375859 Review.
MeSH terms
LinkOut - more resources
Full Text Sources
Miscellaneous