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Case Reports
. 2018 Nov/Dec;93(6):887-889.
doi: 10.1590/abd1806-4841.20187741.

Nodular vasculitis associated with lung adenocarcinoma

Ana Sofia Borges  1 , Ana Brasileiro  1 , Margarida Apetato  1
Affiliations
Case Reports

Nodular vasculitis associated with lung adenocarcinoma

Ana Sofia Borges et al. An Bras Dermatol. 2018 Nov/Dec.

Abstract

Nodular vasculitis is an uncommon type of panniculitis. It was firstly associated to the infection by Mycobacterium tuberculosis and named erythema induratum of Bazin, however nowadays it has been associated with several other underlying disorders and it is better described as nodular vasculitis. Concerning its relationship with malignant conditions, there is only one reported case, in association with metastatic colon adenocarcinoma. We report a case of nodular vasculitis as the first manifestation of lung adenocarcinoma. To the best of our knowledge, this is the first reported association of both diseases.

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Conflict of interest statement

Conflict of interest: None.

Figures

Figure 1
Figure 1
A and B - Bilateral tender erythematous subcutaneous nodules on the lower legs
Figure 2
Figure 2
A - Histopathologic specimen showing predominantly lobular panniculitis with adipocyte necrosis (Hematoxylin & eosin, x40) ; B- Vasculitis of hypodermal vessel with surrounding mixed infiltrate of neutrophils, lymphocytes, and histiocytes (Hematoxylin & eosin, x100)
See this image and copyright information in PMC

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