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. 2016 Sep-Dec;16(3):266-275.
doi: 10.1016/j.ijchp.2016.03.001. Epub 2016 Jun 3.

Psychiatric comorbidities in autism spectrum disorder: A comparative study between DSM-IV-TR and DSM-5 diagnosis

Marina Romero  1   2 , Juan Manuel Aguilar  3 , Ángel Del-Rey-Mejías  4 , Fermín Mayoral  3 , Marta Rapado  4 , Marta Peciña  5 , Miguel Ángel Barbancho  2 , Miguel Ruiz-Veguilla  6 , José Pablo Lara  2
Affiliations

Psychiatric comorbidities in autism spectrum disorder: A comparative study between DSM-IV-TR and DSM-5 diagnosis

Marina Romero et al. Int J Clin Health Psychol. 2016 Sep-Dec.

Abstract
in English, Spanish

Background/Objective: The heterogeneous clinical presentations of individuals with Autism Spectrum Disorders (ASD) pose a significant challenge for sample characterization. Therefore the main goal of DSM-5 must be to identify subgroups of ASD, including comorbidity disorders and severity. The main goal of this study is to explore the psychiatric comorbidities and the severity of symptoms that could be relevant for the phenotype characterization in ASD and also to compare these results according to the different classification criteria between the DSM-IV-TR and the DSM-5. Method: A comparative study of severity and psychiatric comorbidities was carried out between a sample of participants that only met criteria for Pervasive Developmental Disorder (PDD) according to the DSM-IV-TR and a sample of participants that also met ASD criteria according to DSM-5 classification. The recruitment of children was via educational (N = 123). The psychiatric symptoms, comorbid disorders and severity of symptoms were assessed through The Nisonger Child Behavior Rating Form, clinical interview and The Inventory of Autism Spectrum Disorder, respectively. The psychiatric comorbidities considered were: anxiety, eating behavioural problems, self-aggressiveness, hetero-aggressiveness, self-harm, obsessive compulsive disorder and attention deficit and hyperactivity disorder. Results: Statistically significant differences between both groups were found regarding obsessive compulsive disorder, eating behavioural problems and severity. Conclusions: The results support the hypothesis that patients who meet the DSM-5 criteria have more severe symptoms, not only regarding the core autistic symptoms but also in relation with psychiatric comorbidities.

Antecedentes/Objetivo: Los Trastornos del Espectro Autista (TEA) incluyen un grupo heterogéneo en cuanto a su presentación clínica, que supone un desafío a nivel de caracterización diagnóstica. Por consiguiente, el objetivo principal de la clasificación DSM-5 debería de ser identificar subgrupos de TEA incluyendo severidad y comorbilidades psiquiátricas. El objetivo principal de este estudio es explorar las comorbilidades diagnósticas que pueden ser relevantes como descriptores de fenotipos autistas así como la severidad de los síntomas de autismo y comparar los resultados de las diferentes criterios de clasificación entre el DSM-IV-TR y el DSM-5. Método: Se realiza un estudio comparativo de severidad y comorbilidades psiquiátricas entre una muestra con diagnóstico de Trastorno Generalizado del Desarrollo, según criterios DSM-IV-TR, y una muestra que cumplía también criterios para TEA según la clasificación DSM-5. La muestra fue obtenida en centros educativos (N = 123). Las comorbilidades psiquiátricas y la severidad de los síntomas se evaluaron a través del The Nisonger Child Behavior Rating Form, entrevista clínica y el Inventario de Trastorno del Espectro Autista, respectivamente. Las comorbilidades estudiadas fueron ansiedad, alteraciones de la conducta alimentaria, auto-agresividad, hetero-agresividad, autolesiones, trastorno obsesivo-compulsivo y déficit de atención e hiperactividad. Resultados: Se encontraron diferencias estadísticamente significativas entre ambos grupos para trastorno obsesivo-compulsivo, alteraciones de la conducta alimentaria y severidad. Conclusiones: Se apoya la hipótesis de que los individuos que cumplen criterios diagnósticos según DSM-5 tienen mayor severidad sintomática, no sólo con respecto a los síntomas autistas centrales, sino también en relación con comorbilidades psiquiátricas.

Keywords: Autism spectrum disorder; DSM-5; DSM-IV-TR; Descriptive study; Psychiatric-comorbidities.

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Figures

Figure 2
Figure 2
Flow diagram.
Figure 1
Figure 1
Proposed Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) criteria and associated features to be considered when characterizing autism spectrum disorder (ASM) samples (Grzadzinski et al., 2013, with permission).
See this image and copyright information in PMC

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References

    1. Aman M.G., Burrow W.H., Wolford P.L. The Aberrant Behavior Checklist-Community: Factor validity and effect of subject variables for adults in group homes. American Journal of Mental Retardation. 1995;100:283–292. - PubMed
    1. American Psychiatric Association, APA . American Psychiatric Association; Washington. DC: 2013. Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5)
    1. Bandini L.G., Anderson S.E., Curtin C., Cermak S., Evans E.W., Scampini R., Maslin M., Must A. Food selectivity in children with autism spectrum disorders and typically developing children. Journal of Pediatrics. 2010;157:259–264. - PMC - PubMed
    1. Beighley J.S., Matson J.L., Rieske R.D., Jang J., Cervantes P.E., Goldin R.L. Comparing challenging behavior in children diagnosed with autism spectrum disorders according to the DSM-IV-TR and the proposed DSM-5. Developmental Neurorehabilitation. 2013;16:375–381. - PubMed
    1. Bejerot S. An autistic dimension: a proposed subtype of obsessive-compulsive disorder. Autism. 2007;11:101–110. - PubMed