Will ¹⁸F flurpiridaz replace ⁸²rubidium as the most commonly used perfusion tracer for PET myocardial perfusion imaging?

Affiliations

Editorial

Dennis A Calnon. J Nucl Cardiol. 2019 Dec.

. 2019 Dec;26(6):2031-2033.

doi: 10.1007/s12350-017-1153-z. Epub 2018 Nov 28.

¹ OhioHealth Heart and Vascular Physicians, Columbus, USA. dennis.calnon@ohiohealth.com.

No abstract available

Comment on

Dosimetry, biodistribution, and safety of flurpiridaz F 18 in healthy subjects undergoing rest and exercise or pharmacological stress PET myocardial perfusion imaging.
Maddahi J, Bengel F, Czernin J, Crane P, Dahlbom M, Schelbert H, Sparks R, Phelps M, Lazewatsky J. Maddahi J, et al. J Nucl Cardiol. 2019 Dec;26(6):2018-2030. doi: 10.1007/s12350-018-01484-z. Epub 2018 Nov 28. J Nucl Cardiol. 2019. PMID: 30488323

1. Cerqueiera MD, Allman KC, Ficaro EP, Hansen CL, Nichols KJ, Thompson RC, et al. Recommendations for reducing radiation exposure in myocardial perfusion imaging. J Nucl Cardiol. 2010;17:709–18. - DOI
1. Dorbala S, Hachamovitch R, Curillova Z, Vangala D, Kwong RY, DiCarli MF. Incremental prognostic value of gated Rb-82 positron emission tomography myocardial perfusion imaging over clinical variables and rest LVEF. JACC Cardiovasc Imaging. 2009;2:846–54. - DOI
1. McArdle BA, Dowsley TF, DekempRA Wells GA, Beanlands RS. Does rubidium-82 PET have superior accuracy to SPECT perfusion imaging for the diagnosis of obstructive coronary disease? A systematic review and meta-analysis. J Am Coll Cardiol. 2012;60:1828–37. - DOI
1. Lortie M, Beanlands RS, Yoshinaga K, Klein R, Dasilva JN, Dekemp RA. Quantification of myocardial blood flow with ⁸²Rb dynamic PET imaging. Eur J Nucl Med Mol Imaging. 2007;34:1765–74. - DOI
1. Garcia EV, Galt JR, Faber TL, et al. Principles of nuclear cardiology imaging. In: Dilsizian V, Narula J, editors. Atlas of Nuclear Cardiology. 4th ed. New York: Springer; 2013. p. 1–53.