An insect brain peptide as a member of insulin family
- PMID: 3049291
- DOI: 10.1055/s-2007-1010852
An insect brain peptide as a member of insulin family
Abstract
Amino acid sequencing of bombyxin (previously called 4K-PTTH) isolated from the heads of the silkmoth Bombyx mori has disclosed sequence homology of this insect neuropeptide with insulin. Immunohistochemistry using an antibody against a synthetic bombyxin fragment detected 4 pairs of immunoreactive neurosecretory cells in the dorso-medial region of the Bombyx brain. The same cells were reactive to bovine insulin antibody.
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