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. 1988 Oct;170(10):4967-8.
doi: 10.1128/jb.170.10.4967-4968.1988.

Very short patch mismatch repair activity associated with gene dcm is not conferred by a plasmid coding for EcoRII methylase

M Lieb  1 , A S Bhagwat
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Very short patch mismatch repair activity associated with gene dcm is not conferred by a plasmid coding for EcoRII methylase

M Lieb et al. J Bacteriol. 1988 Oct.

Abstract

The only cytosine methylase in Escherichia coli K-12 methylates the second cytosine in the sequence CC (A/T)GG and is encoded by gene dcm. Methylation and very short patch mismatch repair activities lacking in a dcm mutant of E. coli were restored by a plasmid containing the cloned dcm gene. In contrast, plasmids with the gene for EcoRII methylase, which is a homolog of dcm, restored only cytosine methylase activity and not mismatch repair.

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