Rare Cutaneous T-Cell Lymphomas

Abstract

Rare lymphoma includes the entities that occur in less than 1% of cases of all lymphomas. Although the percentage is low, there are more than eight lymphomas classified as rare lymphomas. This article describes clinical presentation, diagnosis, prognosis, and management of the most common rare lymphomas, including primary cutaneous γδ T-cell lymphoma, primary cutaneous CD4⁺ small/medium T-cell lymphoproliferative disorder, primary cutaneous acral CD8⁺ T-cell lymphoma, primary cutaneous CD8⁺ aggressive epidermotropic cytotoxic T-cell lymphoma, extranodal NK-/T-cell lymphoma, nasal type, and subcutaneous panniculitis-like T-cell lymphoma.

Keywords: CD8; Gamma/delta T cells; NK cells; T-cell lymphomas.