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. 2018 Oct;38(5):453-459.
doi: 10.14639/0392-100X-1614.

Prediction of hearing recovery in sudden deafness treated with intratympanic steroids

G Attanasio  1 , F Y Russo  2   3 , E Di Porto  4 , L Cagnoni  2 , E Masci  2 , M Ralli  5 , A Greco  2 , M De Vincentiis  2
Affiliations

Prediction of hearing recovery in sudden deafness treated with intratympanic steroids

G Attanasio et al. Acta Otorhinolaryngol Ital. 2018 Oct.

Abstract
in English, Italian

The present study aims to obtain a probability model allowing prediction of auditory recovery in patients affected by sudden sensorineural hearing loss treated exclusively with intratympanic steroids. A monocentric retrospective chart review of 381 patients has been performed. A Probit model was used to investigate the correlation between the success of treatment (marked or total recovery according to Furuashi's criteria) and the delay between onset of disease and beginning of therapy. The age of patients and audiometric curve shapes were included in the analysis. The results show that delay is negatively correlated with variable success. Considering the entire sample, each day of delay decreases the probability of success by 3%. The prediction model shows that for each day that passes from the onset of the disease the probability of success declines in absence of the medical treatment, hence we conclude that early treatment is strongly recommended.

Previsione delle possibilità di recupero uditivo nell’ipoacusia improvvisa trattata con steroidi intratimpanici.

Riassunto: Il presente studio ha lo scopo di ottenere un modello di probabilità che consenta di prevedere il recupero uditivo nei pazienti affetti da ipoacusia improvvisa neurosensoriale trattati esclusivamente con steroidi intratimpanici. È stata realizzata una revisione retrospettica dei dati di 381 pazienti. Un modello Probit è stato utilizzato per studiare la correlazione tra il successo del trattamento (“marked” or “total recovery” secondo i criteri di Furuashi) e il ritardo (Delay) tra l’insorgenza della malattia e l’inizio della terapia. Sono stati inclusi nell’analisi i dati relativi all’età dei pazienti e alle curve audiometriche. Dallo studio è emerso che la variabile Delay è negativamente correlata con la variabile successo. Considerando l’intero campione, ogni giorno di ritardo diminuisce del 3% la probabilità di successo. Il modello di previsione mostra che per ogni giorno che passa dal momento della comparsa della malattia, la probabilità di successo declina in assenza dell’intervento; possiamo quindi concludere che il trattamento precoce è fortemente raccomandato.

Keywords: Audiometry; Hearing loss; Prognosis; Recovery; Sensorineural; Steroids.

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Figures

Fig. 1.
Fig. 1.
Effect of delay-square variable on the entire sample.
See this image and copyright information in PMC

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