Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Oct 4:2018:2624054.
doi: 10.1155/2018/2624054. eCollection 2018.

Clinical and Demographic Features of Basal Cell Carcinoma in North Jordan

Firas Al-Qarqaz  1 , Maha Marji  1 , Khaldon Bodoor  2 , Rowida Almomani  3 , Wisam Al Gargaz  4 , Diala Alshiyab  1 , Jihan Muhaidat  1 , Mohammad Alqudah  5
Affiliations

Clinical and Demographic Features of Basal Cell Carcinoma in North Jordan

Firas Al-Qarqaz et al. J Skin Cancer. .

Abstract

Basal cell carcinoma (BCC) is the most common cancer affecting humans. It almost has no tendency for metastasis; however it can be destructive to surrounding tissue. Patients with darker skin colors have lower risk of developing skin cancers and the clinical characteristics may differ from populations with lighter skin colors. Methods. This is a retrospective clinical study (2003-2017). Data on age, gender, and location of tumor were collected and analyzed. Results. 335 cases were identified. Males tend to get BCC at a younger age than females. Face was the most common site in both males and females. Cheeks and nose were the most likely areas of the face to be involved. Scalp was the most common extrafacial site to be involved in males; however in females scalp was much less likely to be involved. Conclusion. BCC is less common in populations with darker skin. Males were more affected and at an earlier age compared to females. Facial skin followed by scalp was the most common site affected. Skin phototype, cultural and religious dress type, and different sun exposure behavior may explain many of the clinical and demographic findings related to BCC in patients with darker skin tones.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Map of Jordan showing the geography of the study area.
Figure 2
Figure 2
Number of BCC new cases over 15 years: 2003-2018.
Figure 3
Figure 3
BCC distribution according to site.
See this image and copyright information in PMC

References

    1. Armstrong B. K., Kricker A. The epidemiology of UV induced skin cancer. Journal of Photochemistry and Photobiology B: Biology. 2001;63(1–3):8–18. doi: 10.1016/S1011-1344(01)00198-1. - DOI - PubMed
    1. Rahnama F., Toftgård R., Zaphiropoulos P. G. Distinct roles of PTCH2 splice variants in Hedgehog signalling. Biochemical Journal. 2004;378(2):325–334. doi: 10.1042/bj20031200. - DOI - PMC - PubMed
    1. Parren L., Frank J. Hereditary tumour syndromes featuring basal cell carcinomas. British Journal of Dermatology. 2011;165(1):30–34. doi: 10.1111/j.1365-2133.2011.10334.x. - DOI - PubMed
    1. Marzuka A. G., Book S. E. Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management. Yale Journal of Biology and Medicine. 2015;88(2):167–179. - PMC - PubMed
    1. Mackiewicz-Wysocka M., Bowszyc-Dmochowska M., Strzelecka-Węklar D., Dańczak-Pazdrowska A., Adamski Z. Reviews Basal cell carcinoma – diagnosis. Współczesna Onkologia. 2013;4:337–342. doi: 10.5114/wo.2013.35684. - DOI - PMC - PubMed

LinkOut - more resources