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Clinical Trial
. 1988 Summer;4(2):111-5.
doi: 10.1089/jop.1988.4.111.

Clinical comparison of topical solutions containing trimethoprim in treating ocular surface bacterial infections

G N Foulks  1 , R Austin, G Knowlton
Affiliations
Clinical Trial

Clinical comparison of topical solutions containing trimethoprim in treating ocular surface bacterial infections

G N Foulks et al. J Ocul Pharmacol. 1988 Summer.

Abstract

Thirty-nine patients with bacterial ocular surface infections (conjunctivitis, blepharitis or blepharoconjunctivitis) were evaluated after treatment with a topically applied ophthalmic solution containing trimethoprim. A combination of trimethoprim and polymixin B (TP) produced identical clinical and microbiologic responses when compared to a solution containing, in addition to trimethoprim and polymyxin B, sulfacetamide. The sulfa component was not essential to produce desired clinical and microbiologic results.

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