A Perspective on the Potential Utility of a Viscosupplement Multifunctional Biotherapeutic: Proteoglycan-4: From mere lubricant to regulator of tissue homeostasis and inflammation

James Melrose^{1

2

3

4}

Affiliations

¹ Raymond Purves Bone and Joint Research Laboratory, Kolling Institute, Northern Sydney Local Health District, St. Leonards, NSW 2065, Australia.
² Sydney Medical School, Northern, The University of Sydney, Sydney, NSW 2052, Australia.
³ Faculty of Medicine and Health, The University of Sydney, Royal North Shore Hospital, St. Leonards, NSW 2065, Australia.
⁴ Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW 2052, Australia.

Comment

James Melrose. Bioessays. 2019 Jan.

. 2019 Jan;41(1):e1800215.

doi: 10.1002/bies.201800215. Epub 2018 Nov 30.

James Melrose^{1

2

3

4}

¹ Raymond Purves Bone and Joint Research Laboratory, Kolling Institute, Northern Sydney Local Health District, St. Leonards, NSW 2065, Australia.
² Sydney Medical School, Northern, The University of Sydney, Sydney, NSW 2052, Australia.
³ Faculty of Medicine and Health, The University of Sydney, Royal North Shore Hospital, St. Leonards, NSW 2065, Australia.
⁴ Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW 2052, Australia.

No abstract available

Comment on

Proteoglycan 4: From Mere Lubricant to Regulator of Tissue Homeostasis and Inflammation: Does proteoglycan 4 have the ability to buffer the inflammatory response?
Das N, Schmidt TA, Krawetz RJ, Dufour A. Das N, et al. Bioessays. 2019 Jan;41(1):e1800166. doi: 10.1002/bies.201800166. Epub 2018 Nov 28. Bioessays. 2019. PMID: 30485469 Review.