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Review
. 2018 Nov 29;175(6):1452-1454.
doi: 10.1016/j.cell.2018.11.006.

Putting the Immunologic Brakes on Cancer

Jedd Wolchok  1
Affiliations
Free article
Review

Putting the Immunologic Brakes on Cancer

Jedd Wolchok. Cell. .
Free article

Abstract

The 2018 Nobel Prize in Medicine and Physiology has been awarded to James P. Allison and Tasuku Honjo for their discovery of cancer therapy by inhibition of negative immune regulation. These insights have given rise to a class of medicines that have now entered routine use in the treatment of advanced cancers and have provided a foundation for additional exploration and discovery of pathways critical to modulating the immune response to cancer.

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