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. 1978 Oct;64(2):219-22.
doi: 10.1111/j.1476-5381.1978.tb17292.x.

Occurrence of H1- and H2-histamine receptors in the guinea-pig gall bladder in situ

M Impicciatore

Occurrence of H1- and H2-histamine receptors in the guinea-pig gall bladder in situ

M Impicciatore. Br J Pharmacol. 1978 Oct.

Abstract

1 Histamine has a dual action on the in situ gall bladder of the guinea-pig: a spasmogenic and a relaxant effect mediated through H1- and H2-receptor stimulation respectively. 2 The contracturant action, mimicked by 2-(2-aminoethyl) thiazole (a specific H1-receptor agonist), is blocked by mepyramine and the relaxation, mimicked by dimaprit (a specific H2-receptor agonist), is inhibited by cimetidine.

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References

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