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. 2018 Jul;19(7):e394-e402.
doi: 10.1542/neo.19-7-e394.

Diagnosis and Management of Patent Ductus Arteriosus

Maria Gillam-Krakauer  1 , Jeff Reese  1
Affiliations

Diagnosis and Management of Patent Ductus Arteriosus

Maria Gillam-Krakauer et al. Neoreviews. 2018 Jul.

Abstract

Preterm infants are at increased risk for patent ductus arteriosus (PDA). Prolonged exposure to PDA may be deleterious and has been associated with neonatal morbidity and mortality. Although the molecular mechanisms underlying regulation of postnatal ductus arteriosus closure are not fully understood, clinical experience and research trials have informed recent changes in PDA management strategies and refocused treatment strategies on smaller subsets of infants who require intervention. This review examines current diagnostic and management approaches to PDA in preterm neonates.

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Figures

Figure.
Figure.
Evaluation of patent ductus arteriosus (PDA) with echocardiography. A, B. Left-to-right (L-R) shunt (indicated by arrows) via the ductus produces most of the physical signs and complications related to PDA. C–E.Short-axis andsuprasternal views reveal structural relationships and color Doppler flow patterns indicative of L-R shunt across the ductus arteriosus. Ao=aorta; LPA=left pulmonary artery; MPA=main pulmonary artery. Images adapted or reprinted with permission from Texas Children΄s Hospital,61)(62) and by Creative Commons license.(63)
See this image and copyright information in PMC

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