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. 2018 Jun;4(2):221-236.
doi: 10.1007/s40746-018-0130-3. Epub 2018 Apr 27.

Medical Management of Vascular Anomalies

Reema Padia  1 , Randall Bly  1 , Catherine Bull  1 , Amy E Geddis  2 , Jonathan Perkins  1
Affiliations

Medical Management of Vascular Anomalies

Reema Padia et al. Curr Treat Options Pediatr. 2018 Jun.

Abstract

Purpose of review: This chapter will summarize the most recent literature regarding the current state of medical treatment for vascular anomalies.

Recent findings: Research into the biology of these anomalies has strengthened our understanding of each anomaly and has helped to pave the way for more tailored treatment options involving molecular and/or genetic targets.

Summary: While there is still a role for surgical intervention, medical therapies that target the etiology of vascular anomalies may represent an alternative or adjunctive approach in the management of these lesions.

Keywords: Infantile hemangioma; genetics; lymphatic malformation; propranolol; rapamycin; vascular anomalies.

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Conflict of interest statement

Conflict of Interest: Reema Padia, Catherine Bull, Randall Bly, Amy E. Geddis, and Jonathan Perkins declare no conflicts of interest.

Figures

Figure 1
Figure 1
PI3K/AKT pathway and MEK pathway leading to cell growth and proliferation.
See this image and copyright information in PMC

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