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Case Reports
. 2018 Winter;7(4):183-189.

Optical Rehabilitation of a Patient with Keratoconus and Nystagmus

Dorcas K Tsang  1   2 , Frank Spors  1 , Jie Shen  1 , Lance E McNaughton  1 , Donald J Egan  3
Affiliations
Case Reports

Optical Rehabilitation of a Patient with Keratoconus and Nystagmus

Dorcas K Tsang et al. Med Hypothesis Discov Innov Ophthalmol. 2018 Winter.

Abstract

Keratoconus is a progressive corneal disease characterized by bilateral yet usually asymmetric thinning of the cornea with an onset typically in teenage years. While it often presents as an isolated condition, keratoconus may also be associated with many systemic and/or ocular diseases, such as connective tissue and chromosomal disorders. Its association with nystagmus has been described in Leber's congenital amaurosis, where patients also exhibit abnormal pupillary responses, early-onset retinal dystrophy, mental developmental delays, and eventual blindness. The case described here, however, was a high-functioning teenager with keratoconus and infantile nystagmus, and oscillopsia on left gaze and a compensatory head turn to the patient's left. The initial distance visual acuities of 20/60 and 20/150 in the right and left eye, respectively improved to 20/25 and 20/40 by the use of corneal rigid gas permeable contact lenses. In addition, the patient's neck strain and overall gait were eased by yoked prism spectacles.

Keywords: Ectasia; Infantile Nystagmus; Keratoconus; Rigid Contact Lens; Yoked Prisms.

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Conflict of interest statement

Ethical issues have been completely observed by the authors. All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship of this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval for the version to be published. No conflict of interest has been presented.

Figures

Figure 1
Figure 1
Posterior Segment Optical Coherence Tomography (OCT). Normal Findings of the Right (OD) and Left (OS) Eyes.
Figure 2
Figure 2
Corneal Topography Findings of the Right Eye.
Figure 3
Figure 3
Corneal Topography Findings of the Left Eye.
Figure 4
Figure 4
Corneal Rigid Gas-permeable Contact Lens fitting Pattern, using Sodium Fluorescein.
Figure 5
Figure 5
Yoked Prism Spectacles, Prescribed to Compensate for Head Turn.
Figure 6
Figure 6
Linkage Analysis by Phenotype
See this image and copyright information in PMC

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References

    1. Zadnik K, Barr JT, Gordon MO, Edrington TB. Biomicroscopic signs and disease severity in keratoconus Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study Group. Cornea. 1996;15(2):139–46. pmid: 8925661. - PubMed
    1. Zadnik K, Steger-May K, Fink BA, Joslin CE, Nichols JJ, Rosenstiel CE, et al. Between-eye asymmetry in keratoconus. Cornea. 2002;21(7):671–9. pmid: 12352084. - PubMed
    1. Krachmer JH, Feder RS, Belin MW. Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol. 1984;28(4):293–322. - PubMed
    1. Sharif KW, Casey TA, Coltart J. Prevalence of mitral valve prolapse in keratoconus patients. J R Soc Med. 1992;85(8):446–8. pmid: 1404188. - PMC - PubMed
    1. Robertson I. Keratoconus and the Ehlers-Danlos syndrome: a new aspect of keratoconus. Med J Aust. 1975;1(18):571–3. pmid: 1143149. - PubMed

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