Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Oct 31:3:85.
doi: 10.21037/tgh.2018.10.09. eCollection 2018.

Endoscopic management of perforations, leaks and fistulas

Affiliations
Review

Endoscopic management of perforations, leaks and fistulas

Ritu Raj Singh et al. Transl Gastroenterol Hepatol. .

Abstract

The endoscopic management armamentarium of gastrointestinal disruptions including perforations, leaks, and fistulas has slowly but steadily broadened in recent years. Previously limited to surgical or conservative medical management, innovations in advanced endoscopic techniques like natural orifice transluminal endoscopic surgery (NOTES) have paved the path towards development of endoscopic closure techniques. Early recognition of a gastrointestinal defect is the most important independent variable in determining successful endoscopic closure and patient outcome. Some devices including through the scope clips and stents have been well studied for other indications and have produced encouraging results in closure of gastrointestinal perforations, leaks and fistulas. Over the scope clips, endoscopic sutures, vacuum therapy, glue, and cardiac device occluders are other alternative techniques that can be employed for successful endoscopic closure.

Keywords: Endoscopic closure; cardiac septal defect occluder; endoscopic suturing; fistula; leak; over-the-scope clip (OTSC); perforation.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: NA Kumta: Consultant for Apollo Endosurgery, Boston Scientific, Olympus. The other authors have no conflicts of interest to declare.

Similar articles

Cited by

References

    1. Sato H, Inoue H, Ikeda H, et al. Clinical experience of esophageal perforation occurring with endoscopic submucosal dissection. Dis Esophagus 2014;27:617-22. 10.1111/dote.12125 - DOI - PubMed
    1. Ojima T, Takifuji K, Nakamura M, et al. Complications of endoscopic submucosal dissection for gastric noninvasive neoplasia: an analysis of 647 lesions. Surg Laparosc Endosc Percutan Tech 2014;24:370-374. 10.1097/SLE.0b013e318290132e - DOI - PubMed
    1. Thirumurthi S, Raju GS. Management of polypectomy complications. Gastrointest Endosc Clin N Am 2015;25:335-57. 10.1016/j.giec.2014.11.006 - DOI - PubMed
    1. Zhang LP, Chang R, Matthews BD, et al. Incidence, mechanisms, and outcomes of esophageal and gastric perforation during laparoscopic foregut surgery: a retrospective review of 1,223 foregut cases. Surg Endosc 2014;28:85-90. 10.1007/s00464-013-3167-1 - DOI - PubMed
    1. Nguyen NT, Goldman C, Rosenquist CJ, et al. Laparoscopic versus open gastric bypass: a randomized study of outcomes, quality of life, and costs. Ann Surg 2001;234:279-89; discussion 289-91. 10.1097/00000658-200109000-00002 - DOI - PMC - PubMed