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. 2018 Jul-Sep;62(3):222-227.

Macular pigment density changes in central serous chorioretinopathy

Ruxandra Tudosescu  1 , Cristina Mihaela Alexandrescu  2   3 , Sinziana Luminita Istrate  2   3 , Alexandra Vrapciu  2   4 , Radu Constantin Ciuluvica  4 , Liliana Mary Voinea  2   3
Affiliations

Macular pigment density changes in central serous chorioretinopathy

Ruxandra Tudosescu et al. Rom J Ophthalmol. 2018 Jul-Sep.

Abstract

Aim: To present a series of 2 cases of central serous chorioretinopathy and the changes in the macular pigment optical density during the evolution of the disease. Material and methods: A 32-year-old patient presented himself for blurred vision on his LE. The SD OCT imaging revealed serous macular detachment of the neurosensory retina on the LE. The MPOD results were 0.72 on RE and 0.91 on LE. After treatment and resorption of the subretinal fluid, the MPOD values were 0.72 on the RE and 0.82 on the LE. The second patient was a 36-year-old male with metamorphopsia on LE and serous macular detachment on this eye. The MPOD results were 0.43 on RE and 0.58 on the LE and, after treatment, they were 0.38 on the RE and 0.43 on the LE. Conclusions: Central serous chorioretinopathy is a disease of unknown pathophysiology in which we observed a higher MPOD on the eye with CSC than on the fellow eye and a decrease in the MPOD value after the resorption of the subretinal fluid. Abbreviations: L = lutein, Z = zeaxantin, MZ = mezozeaxantin, AMD = age related macular degeneration, MPOD = macular pigment optical density, MP = macular pigment, HFP = Heterochromatic Flicker Photometry, CSC = central serous chorioretinopathy, RE = right eye, LE = left eye.

Keywords: central serous chorioretinopathy; macular pigment optical density.

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Figures

Fig. 1
Fig. 1
Left eye – serous macular detachment (case 1)
Fig. 2,3
Fig. 2,3
LE - Early and late phase of the angiofluorography with the expansile dot pattern (case 1)
Fig. 4
Fig. 4
OCT of the LE with serous detachment of the neuroretina (case 1)
Fig. 5
Fig. 5
MPOD measurement report before treatment (case 1)
Fig. 6
Fig. 6
MPOD measurement after treatment and with no subretinal fluid (case1)
Fig. 7
Fig. 7
SD OCT of the LE after treatment (case 1)
Fig. 8
Fig. 8
SD OCT of the LE with neurosensory detachment of the retina (case 2)
Fig. 9
Fig. 9
SD OCT of the left eye after resorption of the subretinal fluid (case 2)
Fig. 10
Fig. 10
MPOD measurement after treatment and no subretinal fluid (case 2)
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