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Review
. 2018 Oct 31;4(3):216-221.
doi: 10.1016/j.wjorl.2018.08.004. eCollection 2018 Sep.

The microbiome and chronic rhinosinusitis

Affiliations
Review

The microbiome and chronic rhinosinusitis

Rahuram Sivasubramaniam et al. World J Otorhinolaryngol Head Neck Surg. .

Abstract

Chronic rhinosinusitis (CRS) is a multifactorial condition in which the microbiota plays a pathogenic role. The nature of the interaction between the microbiota and the local immune system is very complex and has not been fully elucidated. Recent improvements in the microbiological techniques have greatly advanced our understanding of the complex nature of this interaction. This paper summarizes the current state of the rapidly evolving research on this subject. Defining the nature of the role of the microbiota in CRS is important because of the associated therapeutic implications.

Keywords: Bacteriology; Inflammation; Microbiome; Pathogenesis; Polyposis; Sinusitis.

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References

    1. Luckey T.D. Introduction to intestinal micro ecology. Am J Clin Nutr. 1972;25:1292–1294. http://www.ncbi.nlm.nih.gov/pubmed/4639749 - PubMed
    1. Bäckhed F., Ley R.E., Sonnenburg J.L., Peterson D.A., Gordon J.I. Host-bacterial mutualism in the human intestine. Science. 2005;307:1915–1920. http://www.ncbi.nlm.nih.gov/pubmed/15790844 - PubMed
    1. Man W.H., de Steenhuijsen Piters W.A., Bogaert D. The microbiota of the respiratory tract: gatekeeper to respiratory health. Nat Rev Microbiol. 2017;15:259–270. http://www.ncbi.nlm.nih.gov/pubmed/28316330 - PMC - PubMed
    1. Eidi S., Kamali S.A., Hajari Z. Nasal and indoors fungal contamination in healthy subjects. Health Scope. 2016;5
    1. Charlson E.S., Diamond J.M., Bittinger K. Lung-enriched organisms and aberrant bacterial and fungal respiratory microbiota after lung transplant. Am J Respir Crit Care Med. 2012;186:536–545. http://www.ncbi.nlm.nih.gov/pubmed/22798321 - PMC - PubMed