Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2018 Nov;97(48):e13391.
doi: 10.1097/MD.0000000000013391.

A comparison of adductor canal block and femoral nerve block after total-knee arthroplasty regarding analgesic effect, effectiveness of early rehabilitation, and lateral knee pain relief in the early stage

Affiliations
Randomized Controlled Trial

A comparison of adductor canal block and femoral nerve block after total-knee arthroplasty regarding analgesic effect, effectiveness of early rehabilitation, and lateral knee pain relief in the early stage

Zhen Tan et al. Medicine (Baltimore). 2018 Nov.

Abstract

Background: The aim of this study was to compare the analgesic effect on the lateral and overall knee and early rehabilitation between adductor canal block (ACB) and femoral nerve block (FNB) after total-knee arthroplasty.

Method: Two hundred patients randomly participated in the study and were divided into the ACB group and FNB group in a randomized manner. All patients received standardized anesthesia and analgesia upon hospitalization. Outcome evaluations included visual analog scale (VAS) scores at rest and during activity, quadriceps strength, range of motion (ROM), total opioid consumption and complication occurrence, sleep interruptions caused by pain, postoperative nausea and vomiting (PONV), and postoperative length of stay (PLOS) before discharge in all groups. In the 90-day postoperative follow-up, we also observed the acute deep periprosthetic joint infection, wound breakdown, readmission, reoperations, inpatient falls, ROM, and patient satisfaction score.

Results: The lateral knee VAS scores are lower in the FNB group at rest and during activity (2-24 hours postoperatively) compared with those in the ACB group. However, the overall knee VAS score, total opioid consumption and complication occurrence, sleep interruptions caused by pain, and PONV are similar between the FNB and ACB groups. When evaluating early rehabilitation, the quadriceps strength in the ACB group is superior to that in the FNB group 24 hours postoperatively. At 24, 48, and 72 hours postoperatively, ROM in the ACB group is significantly better than that in the FNB group. Furthermore, the ACB group has a shorter PLOS (4.5 ± 0.60 days) than the FNB group (5.3 ± 0.7 days). However, patient satisfaction score, readmission rate, inpatient falls, acute deep periprosthetic joint infection, and wound breakdown are not statistically significantly different between the 2 groups.

Conclusion: The ACB does not relieve lateral knee pain in the early stage but provides similar analgesic effect and better effectiveness of early rehabilitation compared with FNB in patients undergoing TKA.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Consort diagram of patients’ randomization, intervention, and analysis.
Figure 2
Figure 2
The VAS scores (A) at rest and (B) during activity of lateral knee of adductor canal block ACB and FNB group at different time points postoperation. Statistical significance was assigned at P < .05, ∗∗∗P < .001. VAS scores (C) at rest and (D) during activity of overall knee of ACB and FNB group at different time points postoperation. There was no statistical difference in VAS scores between the 2 groups at all time points. Two-tailed Student t test was used to compare data. ACB = adductor canal block, 90D = 90-day postoperative, DIS = upon discharge, FNB = femoral nerve block, h = hours, VAS scores = visual analog scale scores.
Figure 3
Figure 3
Quadriceps strength of adductor canal block (ACB) and femoral nerve Block (FNB) group at different time-points postoperation. Two-tailed Student t test was used to compare data and statistical significance was assigned at ∗P < .05, ∗∗∗P < .001. 90D = 90 day postoperation, DIS = upon discharge, h = hours, Kgf = kilogram of force.
Figure 4
Figure 4
Range of motion of adductor canal block (ACB) and femoral nerve block (FNB) group at different time-point postoperation. Two-tailed Student t test was used to compare data and statistical significance was assigned at ∗∗∗P < .001. 90D = 90-day postoperation, DIS = upon discharge, h = hours.

Similar articles

Cited by

References

    1. Parvizi J, Miller AG, Gandhi K. Multimodal pain management after total joint arthroplasty. J Bone Joint Surg Am 2011;93A:1075–84. - PubMed
    1. Vendittoli PA, Makinen P, Drolet P, et al. A multimodal analgesia protocol for total knee arthroplasty - a randomized, controlled study. J Bone Joint Surg Am 2006;88A:282–9. - PubMed
    1. Abdul-Hadi O, Parvizi J, Austin MS, et al. Nonsteroidal anti-inflammatory drugs in orthopaedics. J Bone Joint Surg Am 2009;91A:2020–7. - PubMed
    1. Husted H, Lunn TH, Troelsen A, et al. Why still in hospital after fast-track hip and knee arthroplasty? Acta Orthop 2011;82:679–84. - PMC - PubMed
    1. Barrington MJ, Olive D, Low K, et al. Continuous femoral nerve blockade or epidural analgesia after total knee replacement: a prospective randomized controlled trial. Anesth Analg 2005;101:1824–9. - PubMed

Publication types

Substances