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1 Department of Pediatrics, Division of Pediatric Infectious Diseases, State University of New York Downstate Medical Center, Brooklyn, New York, USA stephan.kohlhoff@downstate.edu.
2 Department of Pediatrics, Division of Pediatric Infectious Diseases, State University of New York Downstate Medical Center, Brooklyn, New York, USA.
1 Department of Pediatrics, Division of Pediatric Infectious Diseases, State University of New York Downstate Medical Center, Brooklyn, New York, USA stephan.kohlhoff@downstate.edu.
2 Department of Pediatrics, Division of Pediatric Infectious Diseases, State University of New York Downstate Medical Center, Brooklyn, New York, USA.
The in vitro activities of omadacycline, azithromycin, doxycycline, moxifloxacin, and levofloxacin were tested against 15 isolates of Chlamydia pneumoniae The minimum inhibitory concentration at which 90% of the isolates of C. pneumoniae were inhibited by omadacycline was 0.25 μg/ml (range, 0.03 to 0.5 μg/ml).
Hammerschlag MR, Kohlhoff SA, Gaydos CA. 2014. Chlamydia pneumoniae, p 2174–2182. In Mandell GL, Bennett JE, Dolin R (ed), Principles and Practice of Infectious Diseases, 8th ed Elsevier, Inc., Philadelphia, PA.
Kohlhoff SA, Hammerschlag MR. 2015. Treatment of chlamydial infections: 2014 update. Expert Opin Pharmacother 16:205–212. doi:10.1517/14656566.2015.999041.
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Pfaller MA, Rhomberg PR, Huband MD, Flamm RK. 2018. Activity of omadacycline tested against Streptococcus pneumoniae from a global surveillance program. Diagn Microbiol Infect Dis 90:143–147. doi:10.1016/j.diagmicrobio.2017.10.010.
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Waites KB, Crabb DM, Lui Y, Duffy LB. 2016. In vitro activities of omadacycline (PTK 0796) and other antimicrobial agents against human mycoplasmas and ureaplasmas. Antimicrob Agents Chemother 60:7502–7504. doi:10.1128/AAC.01734-16.
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Kohlhoff SA, Huband MD, Hammerschlag MR. 2014. In vitro activity of AZD0914, a novel DNA gyrase inhibitor, against Chlamydia trachomatis and Chlamydia pneumoniae. Antimicrob Agents Chemother 58:7595–7596. doi:10.1128/AAC.03920-14.
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