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Review
. 2018 Nov 30;23(12):3164.
doi: 10.3390/molecules23123164.

Chemical Structures of Lignans and Neolignans Isolated from Lauraceae

Ya Li  1 , Shuhan Xie  2 , Jinchuan Ying  3 , Wenjun Wei  4 , Kun Gao  5
Affiliations
Review

Chemical Structures of Lignans and Neolignans Isolated from Lauraceae

Ya Li et al. Molecules. .

Abstract

Lauraceae is a good source of lignans and neolignans, which are the most chemotaxonomic characteristics of many species of the family. This review describes 270 naturally occurring lignans and neolignans isolated from Lauraceae.

Keywords: Lauraceae; chemical components; chemical structures; lignans; neolignans.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Subtypes of classical lignans.
Figure 2
Figure 2
Chemical structures of simple lignans.
Figure 3
Figure 3
Chemical structures of 7,7’-epoxylignans.
Figure 4
Figure 4
Chemical structures of 7,9’-epoxylignans, lignan-9,9’-olides, and 2.9,2’.9’-diepoxylignans.
Figure 5
Figure 5
Chemical structures of 7.9’,7’.9-diepoxylignans.
Figure 6
Figure 6
Chemical structures of 2,7’-cyclolignans.
Figure 7
Figure 7
Subtypes of neolignans.
Figure 8
Figure 8
Chemical structures of 8,1’-neolignans.
Figure 9
Figure 9
Chemical structures of 8,3’-neolignans.
Figure 10
Figure 10
Chemical structures of 7,1’-neolignans.
Figure 11
Figure 11
Subtypes of cycloneolignans.
Figure 12
Figure 12
Chemical structures of 7.3’,8.1’-cycloneolignans.
Figure 13
Figure 13
Chemical structures of 7.3’,8.5’-cycloneolignans.
Figure 14
Figure 14
Chemical structures of 7.1’,8.3’-cycloneolignans.
Figure 15
Figure 15
Subtypes of oxyneolignans.
Figure 16
Figure 16
Chemical structures of 7.3’,8.4’-dioxyneolignans.
Figure 17
Figure 17
Chemical structures of 8,4’-oxyneolignans.
Figure 18
Figure 18
Chemical structures of uncommon neolignans.
See this image and copyright information in PMC

References

    1. Teponno R.B., Kusari S., Spiteller M. Recent advances in research on lignans and neolignans. Nat. Prod. Rep. 2016;33:1044–1094. doi: 10.1039/C6NP00021E. - DOI - PubMed
    1. Shimomura H., Sashida Y., Oohara M. Lignans from Machilus thunbergii. Phytochemistry. 1987;26:1513–1515. doi: 10.1016/S0031-9422(00)81847-6. - DOI
    1. Yu Y.U., Kang S.Y., Park H.Y., Sung S.H., Lee E.J., Kim S.Y., Kim Y.C. Antioxidant lignans from Machilus thunbergii protect CCl4–injured primary cultures of rat hepatocytes. J. Pharm. Pharmacol. 2000;52:1163–1169. doi: 10.1211/0022357001774949. - DOI - PubMed
    1. Ma C.J., Sung S.H., Kim Y.C. Neuroprotective lignans from the bark of Machilus thunbergii. Planta Med. 2004;70:79–80. - PubMed
    1. Li G., Lee C.S., Woo M.H., Lee S.H., Chang H.W., Son J.K. Lignans from the bark of Machilus thunbergii and their DNA topoisomerases I and II inhibition and cytotoxicity. Biol. Pharm. Bull. 2004;27:1147–1150. doi: 10.1248/bpb.27.1147. - DOI - PubMed

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