Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Dec 3:73:e721.
doi: 10.6061/clinics/2017/e721.

Review of a three-year study on the dental care of onco-hematological pediatric patients

Affiliations
Review

Review of a three-year study on the dental care of onco-hematological pediatric patients

Alexandre Viana Frascino et al. Clinics (Sao Paulo). .

Abstract

The aim of this study was to provide an updated review of dental procedures undertaken at the dental unit of the Onco-hematology service of the Instituto da Criança at the Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (ICr/HC-FMUSP). We retrospectively reviewed 565 of 1902 medical and dental records of patients diagnosed with onco-hematological diseases who were seen in a 3-year study (January 2015 to December 2017). We assessed data regarding population characteristics, onco-hematological diagnosis and dental procedures performed. Of the selected medical records, preventive dentistry was the most common procedure undertaken in this population, followed by oral maxillofacial surgeries, restorative dentistry and oral mucositis treatment. The most prevalent malignant diagnosis was acute lymphocytic leukemia, and the most prevalent nonmalignant diagnosis was sickle-cell anemia. Preventive dental procedures represent most of the dental procedures undertaken in hospitalized onco-hematological pediatric patients.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest was reported.

Figures

Figure 1
Figure 1
Inclusion/exclusion criteria flowchart for the selection of medical records and distribution of medical diagnosis.
Figure 2
Figure 2
Age distribution of the study population. The prevalence of age groups in children most commonly affected by each type of cancer in the study population.
Figure 3
Figure 3
Distribution of malignant diagnoses. ALL: acute lymphocytic leukemia; AML acute myeloblastic leukemia. “Other” refers to chronic lymphocytic leukemia, B-cell lymphoma and lymphoblastic lymphoma.
Figure 4
Figure 4
Distribution of nonmalignant diagnoses. Sickle-cell anemia was the most prevalent diagnosis among the nonmalignant diseases.
Figure 5
Figure 5
Dental procedures performed in malignant and nonmalignant patients (%). Distribution of dental procedures showing the proportions of malignant and nonmalignant groups.
Figure 6
Figure 6
Annual distribution of dental procedures.

Similar articles

References

    1. Essig S, Li Q, Chen Y, Hitzler J, Leisenring W, Greenberg M, et al. Estimating the risk for late effects of therapy in children newly diagnosed with standard risk acute lymphoblastic leukemia using an historical cohort: A report from the Childhood Cancer Survivor Study. Lancet Oncol. 2014;15((8)):841–51. doi: 10.1016/S1470-2045(14)70265-7. - DOI - PMC - PubMed
    1. Zinter MS, Holubkov R, Steurer MA, Dvorak CC, Duncan CN, Sapru A, et al. Pediatric Hematopoietic Cell Transplant Patients Who Survive Critical Illness Frequently Have Significant but Recoverable Decline in Functional Status. Biol Blood Marrow Transplant. 2018;24((2)):330–6. doi: 10.1016/j.bbmt.2017.10.036. - DOI - PMC - PubMed
    1. Eduardo FP, Bezinelli LM, Gobbi MF, Pereira AZ, Vogel C, Hamerschlak N, et al. Impact of Oral and Gastrointestinal Mucositis on Body Weight Alterations during Hematopoietic Stem Cell Transplantation. Nutr Cancer. 2018;70((2)):241–8. doi: 10.1080/01635581.2018.1412476. - DOI - PubMed
    1. Miano M, Faraci M, Dini G, Bordigoni P, EBMT Paediatric Working Party. Early complications following haematopoietic SCT in children. Bone Marrow Transplant. 2008;41((Suppl 2)):S39–42. doi: 10.1038/bmt.2008.53. - DOI - PubMed
    1. Leppla L, De Geest S, Fierz K, Deschler-Baier B, Koller A. An oral care self-management support protocol (OrCaSS) to reduce oral mucositis in hospitalized patients with acute myeloid leukemia and allogeneic hematopoietic stem cell transplantation: a randomized controlled pilot study. Support Care Cancer. 2016;24((2)):773–82. doi: 10.1007/s00520-015-2843-1. - DOI - PubMed