Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Famotidine

Preeti Patel, Rajni Ahlawat  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Famotidine

Preeti Patel et al.
Free Books & Documents

Excerpt

Famotidine is a histamine-2 (H2) receptor antagonist that reduces gastric acid secretion and is used to treat gastrointestinal conditions associated with excess acid production. The drug is available both by prescription and over the counter (OTC). Prescription indications for famotidine, as approved by the US Food and Drug Administration (FDA), include the treatment of duodenal and gastric ulcers, gastroesophageal reflux disease in adults and children, and pathological hypersecretory conditions in adults. OTC formulations are approved for the prevention and treatment of heartburn associated with GERD in both adult and pediatric populations.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Preeti Patel declares no relevant financial relationships with ineligible companies.

Disclosure: Rajni Ahlawat declares no relevant financial relationships with ineligible companies.

References

    1. McCullough AJ, Graham DY, Knuff TE, Lanza FL, Levenson HL, Lyon DT, Munsell WP, Perozza J, Roufail WM, Sinar DR. Suppression of nocturnal acid secretion with famotidine accelerates gastric ulcer healing. Gastroenterology. 1989 Oct;97(4):860-6. - PubMed
    1. Vinayek R, Howard JM, Maton PN, Wank SA, Slaff JI, Gardner JD, Jensen RT. Famotidine in the therapy of gastric hypersecretory states. Am J Med. 1986 Oct 24;81(4B):49-59. - PubMed
    1. Keithley JK. Histamine H2-receptor antagonists. Nurs Clin North Am. 1991 Jun;26(2):361-73. - PubMed
    1. Nonprescription version of famotidine wins FDA approval. Am J Health Syst Pharm. 1995 Jul 01;52(13):1377. - PubMed
    1. Hudson N, Taha AS, Russell RI, Trye P, Cottrell J, Mann SG, Swanell AJ, Sturrock RD, Hawkey CJ. Famotidine for healing and maintenance in nonsteroidal anti-inflammatory drug-associated gastroduodenal ulceration. Gastroenterology. 1997 Jun;112(6):1817-22. - PubMed

Publication types

LinkOut - more resources